Click and release of biomolecules

Schneider et al. display that biomolecules can be attached to the surface of TurboBeads by click chemistry, and in a second step can be released unharmed from the particle surface by the use of a mild release agent (buffered oxide etch). Both chemistries (click chemistry and Si-F) are fully orthogonal to standard biochemical reactions.

Schneider et al. Chem. Commun. 2016 (link)