Magnetically recyclable enantioselective Cu catalyst

Schätz et al. functionalized TurboBeads with azabis-(oxazoline)-copper(II) complexes via an azide (“click”) reaction. The catalytic performance for the enantioselctive benzoylation of diols was addressed in batch and continuous flow reactors. In the continuous flow reactor a high degree of agitation was achieved, as a rotating magnetic field was applied in the reaction chamber. This led to a magnetically fixated, moving catalyst bed with highly increased mass transfer rates.

Schätz et al. Chem. Mater. 2010 (link)